Brief Information of the Compound and Protein
Compound Name
 Compound Info 
6-[difluoro-[8-fluoro-6-(1-methylpyrazol-4-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]methyl]quinoline
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 PubChem ID
CID: 44181460
SID: 85170631
Canonical SMILES
Cn1cc(cn1)-c1cc(F)c2nnc(n2c1)C(F)(F)c1ccc2ncccc2c1
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Compound Formula C20H13F3N6
Compound Structure
Protein Name
 Protein Info 
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000048 PC-3
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 15 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 22 nM