Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-(1H-indol-7-ylamino)-3-((1R,2S)-2-aminocyclohexylamino)-1,2,4-triazine-6-carboxamide
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 PubChem ID
CID: 72202597
Canonical SMILES
NC(=O)c1nnc(N[C@@H]2CCCC[C@@H]2N)nc1Nc1cccc2cc[nH]c12
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Compound Formula C18H22N8O
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase ZAP-70
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Syk family
Uniprot ID
P43403
Gene Name
ZAP70
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000001 Jurkat
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 2526 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 251 nM
2 Kd = 65 nM