Brief Information of the Compound and Protein
Compound Name
1-(3-chlorophenyl)-1-(2-hydroxyethyl)-3-[4-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl]urea
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PubChem ID
CID: 118732095
Canonical SMILES
Cc1c[nH]c2ncnc(-c3ccc(NC(=O)N(CCO)c4cccc(Cl)c4)cc3)c12
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Compound Formula C22H20ClN5O2
Compound Structure
Protein Name
LIM domain kinase 1
Protein Classification
Enzyme
>
Kinase
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Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase LISK family
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TKL protein kinase LIMK subfamily
Uniprot ID
P53669
Gene Name
LIMK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000238 A7r5 Rattus norvegicus (Rat)  1
1
IC50 = 372 nM
   TI
   LI
   LO
   TS