Brief Information of the Compound and Protein
Compound Name
1-(4-chlorophenyl)-3-[4-(5,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-2-fluorophenyl]-1-(2-methoxyethyl)urea
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PubChem ID
CID: 118732109
Canonical SMILES
COCCN(C(=O)Nc1ccc(cc1F)-c1ncnc2[nH]c(C)c(C)c12)c1ccc(Cl)cc1
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Compound Formula C24H23ClFN5O2
Compound Structure
Protein Name
LIM domain kinase 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase LISK family
>
TKL protein kinase LIMK subfamily
Uniprot ID
P53669
Gene Name
LIMK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000238 A7r5 Rattus norvegicus (Rat)  1
1
IC50 = 250 nM
   TI
   LI
   LO
   TS