Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-methyl-4-[2-[2-methyl-1-(3-methylsulfonylphenyl)imidazol-4-yl]ethynyl]pyridine
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 PubChem ID
CID: 118732220
Canonical SMILES
Cc1nc(cn1-c1cccc(c1)S(C)(=O)=O)C#Cc1ccnc(C)c1
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Compound Formula C19H17N3O2S
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 100 nM
   TI
   LI
   LO
   TS
2
Ki = 252 nM
   TI
   LI
   LO
   TS