Brief Information of the Compound and Protein
Compound Name
4-[2-[1-(4-fluorophenyl)-2-methylimidazol-4-yl]ethynyl]-2-methylpyridine
    Show/Hide
PubChem ID
CID: 10085660
SID: 15072292
Canonical SMILES
Cc1nc(cn1-c1ccc(F)cc1)C#Cc1ccnc(C)c1
    Show/Hide
Compound Formula C18H14FN3
Compound Structure
Protein Name
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
>
Small molecule receptor (family C GPCR)
>
Neurotransmitter receptor (family C GPCR)
>
Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 28 nM
   TI
   LI
   LO
   TS
2
Ki = 22 nM
   TI
   LI
   LO
   TS