Brief Information of the Compound and Protein
Compound Name
3-(2-phenylethynyl)-4H-imidazo[5,1-c][1,4]benzoxazine
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PubChem ID
CID: 9965311
SID: 14942182
Canonical SMILES
C1Oc2ccccc2-n2cnc(C#Cc3ccccc3)c12
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Compound Formula C18H12N2O
Compound Structure
Protein Name
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 161 nM
   TI
   LI
   LO
   TS
2
Ki = 69 nM
   TI
   LI
   LO
   TS