Brief Information of the Compound and Protein
Compound Name
1-(4-fluorophenyl)-3-[4-[4-(methylsulfonylmethyl)-6-morpholin-4-ylpyrimidin-2-yl]phenyl]urea
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PubChem ID
CID: 24804985
SID: 49751162
Canonical SMILES
CS(=O)(=O)Cc1cc(nc(n1)-c1ccc(NC(=O)Nc2ccc(F)cc2)cc1)N1CCOCC1
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Compound Formula C23H24FN5O4S
Compound Structure
Protein Name
Serine/threonine-protein kinase mTOR
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Atypical protein kinase group
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Atypical protein kinase PIKK family
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Atypical protein kinase FRAP subfamily
Uniprot ID
P42345
Gene Name
MTOR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 28 nM
   TI
   LI
   LO
   TS
2
IC50 = 28.18 nM
   TI
   LI
   LO
   TS