Brief Information of the Compound and Protein
Compound Name
N-[2-[(3-chloro-2-fluorophenyl)methylsulfanyl]-6-[[(2R)-1-hydroxypropan-2-yl]amino]pyrimidin-4-yl]-1-methylimidazole-4-sulfonamide
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PubChem ID
CID: 10345330
SID: 15356844
Canonical SMILES
C[C@H](CO)Nc1cc(NS(=O)(=O)c2cn(C)cn2)nc(SCc2cccc(Cl)c2F)n1
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Compound Formula C18H20ClFN6O3S2
Compound Structure
Protein Name
C-X-C chemokine receptor type 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Chemokine receptor
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CXC chemokine receptor
Uniprot ID
P25025
Gene Name
CXCR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 12.59 nM
   TI
   LI
   LO
   TS
2
Kd = 199.53 nM
   TI
   LI
   LO
   TS