Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2S)-2-amino-4-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methylsulfanyl]-N-[(5-benzyl-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-2-yl)methyl]butanamide
    Show/Hide
 PubChem ID
CID: 118726596
Canonical SMILES
N[C@@H](CCSC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(=O)NCc1cc2CN(Cc3ccccc3)CCn2n1
    Show/Hide
Compound Formula C28H36N10O4S
Compound Structure
Protein Name
 Protein Info 
Histone-lysine N-methyltransferase EZH2
Protein Classification
Epigenetic regulator
>
Writer
>
Protein methyltransferase
Uniprot ID
Q15910
Gene Name
EZH2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 2800 nM
   TI
   LI
   LO
   TS
2
IC50 = 8000 nM
   TI
   LI
   LO
   TS