Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(S)-2-amino-4-(((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methylthio)-N-((5-tert-butyl-1H-pyrazol-3-yl)methyl)butanamide
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 PubChem ID
CID: 118726599
Canonical SMILES
CC(C)(C)c1cc(CNC(=O)[C@@H](N)CCSC[C@H]2O[C@@H](n3cnc4c(N)ncnc43)[C@H](O)[C@@H]2O)n[nH]1
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Compound Formula C22H33N9O4S
Compound Structure
Protein Name
 Protein Info 
Histone-lysine N-methyltransferase EZH2
Protein Classification
Epigenetic regulator
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Writer
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Protein methyltransferase
Uniprot ID
Q15910
Gene Name
EZH2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 3600 nM
   TI
   LI
   LO
   TS
2
IC50 = 14000 nM
   TI
   LI
   LO
   TS