Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(S)-2-amino-4-(((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methylthio)-N-((5-phenyl-1H-pyrazol-3-yl)methyl)butanamide
    Show/Hide
 PubChem ID
CID: 118726601
Canonical SMILES
Nc1ncnc2c1ncn2[C@@H]1O[C@H](CSCC[C@H](N)C(=O)NCc2cc(-c3ccccc3)[nH]n2)[C@@H](O)[C@H]1O
    Show/Hide
Compound Formula C24H29N9O4S
Compound Structure
Protein Name
 Protein Info 
Histone-lysine N-methyltransferase EZH2
Protein Classification
Epigenetic regulator
>
Writer
>
Protein methyltransferase
Uniprot ID
Q15910
Gene Name
EZH2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 70 nM
   TI
   LI
   LO
   TS
2
IC50 = 270 nM
   TI
   LI
   LO
   TS