Brief Information of the Compound and Protein
Compound Name
3-[(2S)-3-[benzyl(butyl)amino]-2-hydroxypropyl]-8-(cyclooctylmethyl)-1-(4-fluorophenyl)-1,3,8-triazaspiro[4.5]decan-4-one
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PubChem ID
CID: 23542099
Canonical SMILES
CCCCN(C[C@H](O)CN1CN(c2ccc(F)cc2)C2(CCN(CC3CCCCCCC3)CC2)C1=O)Cc1ccccc1
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Compound Formula C36H53FN4O2
Compound Structure
Protein Name
Kappa-type opioid receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Opioid receptor
Uniprot ID
P41145
Gene Name
OPRK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 240 nM
   TI
   LI
   LO
   TS