Brief Information of the Compound and Protein
Compound Name
8-(cyclooctylmethyl)-3-[(2R)-3-[2-(3,4-dimethoxyphenyl)ethoxy]-2-hydroxypropyl]-1-(4-fluorophenyl)-1,3,8-triazaspiro[4.5]decan-4-one
    Show/Hide
PubChem ID
CID: 23542106
Canonical SMILES
COc1ccc(CCOC[C@H](O)CN2CN(c3ccc(F)cc3)C3(CCN(CC4CCCCCCC4)CC3)C2=O)cc1OC
    Show/Hide
Compound Formula C35H50FN3O5
Compound Structure
Protein Name
Nociceptin receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Opioid receptor
Uniprot ID
P41146
Gene Name
OPRL1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 82 nM
   TI
   LI
   LO
   TS