Brief Information of the Compound and Protein
Compound Name
(2R)-2-amino-N-[(2S)-3-[8-(cyclooctylmethyl)-1-(4-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-3-yl]-2-hydroxypropyl]-3-methyl-N-[(4-methylphenyl)methyl]butanamide
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PubChem ID
CID: 118726273
Canonical SMILES
CC(C)[C@@H](N)C(=O)N(C[C@H](O)CN1CN(c2ccc(F)cc2)C2(CCN(CC3CCCCCCC3)CC2)C1=O)Cc1ccc(C)cc1
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Compound Formula C38H56FN5O3
Compound Structure
Protein Name
Nociceptin receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Opioid receptor
Uniprot ID
P41146
Gene Name
OPRL1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 18 nM
   TI
   LI
   LO
   TS