Brief Information of the Compound and Protein
Compound Name
8-(cyclooctylmethyl)-1-(4-fluorophenyl)-3-[(2R)-2-hydroxy-3-(3-methylphenyl)sulfanylpropyl]-1,3,8-triazaspiro[4.5]decan-4-one
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PubChem ID
CID: 118726272
Canonical SMILES
Cc1cccc(SC[C@H](O)CN2CN(c3ccc(F)cc3)C3(CCN(CC4CCCCCCC4)CC3)C2=O)c1
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Compound Formula C32H44FN3O2S
Compound Structure
Protein Name
Nociceptin receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Opioid receptor
Uniprot ID
P41146
Gene Name
OPRL1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 37 nM
   TI
   LI
   LO
   TS