Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[(4S)-2-amino-7'-(2-fluoropyridin-3-yl)spiro[5H-1,3-oxazole-4,5'-chromeno[2,3-b]pyridine]-3'-yl]benzonitrile
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 PubChem ID
CID: 89998034
Canonical SMILES
NC1=N[C@@]2(CO1)c1cc(ccc1Oc1ncc(cc21)-c1ccc(cc1)C#N)-c1cccnc1F
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Compound Formula C26H16FN5O2
Compound Structure
Protein Name
 Protein Info 
Beta-secretase 1
Protein Classification
Enzyme
>
Protease
>
Aspartic protease
>
Aspartic protease AA clan
>
Aspartic protease A1A subfamily
Uniprot ID
P56817
Gene Name
BACE1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 8.2 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.8 nM