Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-(3-methoxy-4-methylphenyl)-5-(4-piperazin-1-ylphenyl)pyridin-2-amine
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 PubChem ID
CID: 118392567
Canonical SMILES
COc1cc(ccc1C)-c1cc(cnc1N)-c1ccc(cc1)N1CCNCC1
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Compound Formula C23H26N4O
Compound Structure
Protein Name
 Protein Info 
TGF-beta receptor type-1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase STKR family
>
TKL protein kinase STKR Type 1 subfamily
Uniprot ID
P36897
Gene Name
TGFBR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 35500 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 21000 nM