Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-carbamoyl-2-[(5S)-9-fluoro-2-[4-[(3S)-3-fluoropyrrolidine-1-carbonyl]phenyl]-5H-chromeno[2,3-b]pyridin-5-yl]-2-methylpropanamide
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 PubChem ID
CID: 118707982
Canonical SMILES
CC(C)([C@@H]1c2ccc(nc2Oc2c(F)cccc12)-c1ccc(cc1)C(=O)N1CC[C@H](F)C1)C(=O)NC(N)=O
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Compound Formula C28H26F2N4O4
Compound Structure
Protein Name
 Protein Info 
Glucocorticoid receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
>
Nuclear hormone receptor subfamily 3 group C member 1
Uniprot ID
P04150
Gene Name
NR3C1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 0.6 nM
   TI
   LI
   LO
   TS
2
EC50 = 0.8 nM
   TI
   LI
   LO
   TS
CL000017 HeLa
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 1.3 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 1.2 nM