Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[(5S)-5-(1-acetamido-2-methyl-1-oxopropan-2-yl)-9-fluoro-5H-chromeno[2,3-b]pyridin-2-yl]-N,N-dimethylbenzamide
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 PubChem ID
CID: 117917077
Canonical SMILES
CN(C)C(=O)c1ccc(cc1)-c1ccc2[C@H](c3cccc(F)c3Oc2n1)C(C)(C)C(=O)NC(C)=O
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Compound Formula C27H26FN3O4
Compound Structure
Protein Name
 Protein Info 
Glucocorticoid receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
>
Nuclear hormone receptor subfamily 3 group C member 1
Uniprot ID
P04150
Gene Name
NR3C1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 109.1 nM
   TI
   LI
   LO
   TS
2
EC50 = 212.6 nM
   TI
   LI
   LO
   TS
CL000017 HeLa
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 1046 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 1892 nM
2 Ki = 69.4 nM