Brief Information of the Compound and Protein
Compound Name
3-[5-(4-fluorophenyl)-3-methyl-4-(3-oxo-4H-1,4-benzoxazin-6-yl)pyrazol-1-yl]propanenitrile
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PubChem ID
CID: 59281416
Canonical SMILES
Cc1nn(CCC#N)c(c1-c1ccc2OCC(=O)Nc2c1)-c1ccc(F)cc1
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Compound Formula C21H17FN4O2
Compound Structure
Protein Name
Progesterone receptor
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 3
Uniprot ID
P06401
Gene Name
PGR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 4600 nM
   TI
   LI
   LO
   TS
2
IC50 = 5700 nM
   TI
   LI
   LO
   TS