Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}phenyl)formamido]pentanedioic acid
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 PubChem ID
CID: 126941
SID: 14760074
Canonical SMILES
CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(cc1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
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Compound Formula C20H22N8O5
Compound Structure
Protein Name
 Protein Info 
Proton-coupled folate transporter
Protein Classification
Transporter
>
Electrochemical transporter
>
SLC superfamily of solute carriers
>
SLC46 family of folate transporters
Uniprot ID
Q96NT5
Gene Name
SLC46A1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000937 R2/PCFT4
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 120.5 nM
   TI
   LI
   LO
   TS
2
IC50 = 121 nM
   TI
   LI
   LO
   TS