Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-(4-cyanophenyl)-3-[3-(6-pyrrolidin-1-ylpyridin-2-yl)phenyl]urea
    Show/Hide
 PubChem ID
CID: 118716114
Canonical SMILES
O=C(Nc1ccc(cc1)C#N)Nc1cccc(c1)-c1cccc(n1)N1CCCC1
    Show/Hide
Compound Formula C23H21N5O
Compound Structure
Protein Name
 Protein Info 
Cannabinoid receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
>
Cannabinoid receptor
Uniprot ID
P21554
Gene Name
CNR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000076 CHO/Galpha16
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 33 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 55.2 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 33 nM