Brief Information of the Compound and Protein
Compound Name
2,6-dimethyl-N-[4-(trifluoromethyl)phenyl]furo[2,3-d]pyrimidin-4-amine
    Show/Hide
PubChem ID
CID: 90645481
Canonical SMILES
Cc1cc2c(Nc3ccc(cc3)C(F)(F)F)nc(C)nc2o1
    Show/Hide
Compound Formula C15H12F3N3O
Compound Structure
Protein Name
Platelet-derived growth factor receptor beta
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P09619
Gene Name
PDGFRB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000004 SH-SY5Y Homo sapiens (Human)  1
1
IC50 = 66.1 nM
   TI
   LI
   LO
   TS