Brief Information of the Compound and Protein
Compound Name
(S)-N-(1-(3-chloro-4-fluorophenyl)-2-hydroxyethyl)-2-(isobutylamino)-5,6-dihydropyrido[3,4-d]pyrimidine-7(8H)-carboxamide
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PubChem ID
CID: 118369772
Canonical SMILES
CC(C)CNc1ncc2c(n1)CN(C(=O)N[C@H](CO)c1ccc(F)c(Cl)c1)CC2
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Compound Formula C20H25ClFN5O2
Compound Structure
Protein Name
Mitogen-activated protein kinase 1
Protein Classification
Enzyme
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Kinase
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Protein Kinase
>
CMGC protein kinase group
>
CMGC protein kinase MAPK family
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CMGC protein kinase ERK subfamily
Uniprot ID
P28482
Gene Name
MAPK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000063 Hep-G2 Homo sapiens (Human)  1
1
IC50 = 513 nM
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