Brief Information of the Compound and Protein
Compound Name
N-[(1S,2S)-1-(3-chloro-4-fluorophenyl)-2-hydroxybutyl]-2-(propan-2-ylamino)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidine-7-carboxamide
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PubChem ID
CID: 90645267
Canonical SMILES
CC[C@H](O)[C@@H](NC(=O)N1CCc2cnc(NC(C)C)nc2C1)c1ccc(F)c(Cl)c1
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Compound Formula C21H27ClFN5O2
Compound Structure
Protein Name
Mitogen-activated protein kinase 1
Protein Classification
Enzyme
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Kinase
>
Protein Kinase
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CMGC protein kinase group
>
CMGC protein kinase MAPK family
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CMGC protein kinase ERK subfamily
Uniprot ID
P28482
Gene Name
MAPK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000063 Hep-G2 Homo sapiens (Human)  1
1
IC50 = 108 nM
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