Brief Information of the Compound and Protein
Compound Name
N-[(1S)-1-(3-chloro-4-fluorophenyl)-2-hydroxyethyl]-2-(oxan-4-ylamino)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidine-7-carboxamide
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PubChem ID
CID: 60198532
SID: 144216203
Canonical SMILES
OC[C@@H](NC(=O)N1CCc2cnc(NC3CCOCC3)nc2C1)c1ccc(F)c(Cl)c1
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Compound Formula C21H25ClFN5O3
Compound Structure
Protein Name
Mitogen-activated protein kinase 1
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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CMGC protein kinase group
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CMGC protein kinase MAPK family
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CMGC protein kinase ERK subfamily
Uniprot ID
P28482
Gene Name
MAPK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000063 Hep-G2 Homo sapiens (Human)  1
1
IC50 = 45 nM
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