Brief Information of the Compound and Protein
Compound Name
1-[(4aR,8S,8aR)-4-benzyl-8-pyrrolidin-1-yl-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]-2-(3,4-dichlorophenyl)ethanone
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PubChem ID
CID: 90645383
Canonical SMILES
Clc1ccc(CC(=O)N2CCN(Cc3ccccc3)[C@@H]3CCC[C@@H]([C@@H]23)N2CCCC2)cc1Cl
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Compound Formula C27H33Cl2N3O
Compound Structure
Protein Name
Kappa-type opioid receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Opioid receptor
Uniprot ID
P41145
Gene Name
OPRK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
EC50 = 29 nM
   TI
   LI
   LO
   TS
2
EC50 = 490 nM
   TI
   LI
   LO
   TS