Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2S)-2-[[(2R)-2-[[(2S)-2-acetamido-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(4-iodophenyl)propanoyl]amino]-N-[(2S)-1-amino-3-(4-iodophenyl)-1-oxopropan-2-yl]-5-(diaminomethylideneamino)pentanamide
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 PubChem ID
CID: 90643803
Canonical SMILES
CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(I)cc1)C(N)=O
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Compound Formula C32H40I2N10O5
Compound Structure
Protein Name
 Protein Info 
Melanocortin receptor 4
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Melanocortin receptor
Uniprot ID
P32245
Gene Name
MC4R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  6
1
EC50 = 0.12 nM
   TI
   LI
   LO
   TS
2
EC50 = 1.5 nM
   TI
   LI
   LO
   TS
3
EC50 = 2.9 nM
   TI
   LI
   LO
   TS
4
EC50 = 3.2 nM
   TI
   LI
   LO
   TS
5
EC50 = 4 nM
   TI
   LI
   LO
   TS
6
EC50 > 100000 nM
   TI
   LI
   LO
   TS