Brief Information of the Compound and Protein
Compound Name
3-[(1R)-1-[5-fluoro-2-(triazol-2-yl)phenyl]ethoxy]-5-(2-methoxypyridin-3-yl)pyrazin-2-amine
    Show/Hide
PubChem ID
CID: 89713230
Canonical SMILES
COc1ncccc1-c1cnc(N)c(O[C@H](C)c2cc(F)ccc2-n2nccn2)n1
    Show/Hide
Compound Formula C20H18FN7O2
Compound Structure
Protein Name
ALK tyrosine kinase receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase STKR family
>
TKL protein kinase STKR Type 1 subfamily
Uniprot ID
Q9UM73
Gene Name
ALK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  2
1
IC50 = 9.7 nM
   TI
   LI
   LO
   TS
2
IC50 = 53 nM
   TI
   LI
   LO
   TS