Brief Information of the Compound and Protein
Compound Name
2-[(1R)-1-[2-amino-5-(1,3-dimethylpyrazol-4-yl)pyridin-3-yl]oxyethyl]-4-fluoro-N-methylbenzamide
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PubChem ID
CID: 90644194
Canonical SMILES
CNC(=O)c1ccc(F)cc1[C@@H](C)Oc1cc(cnc1N)-c1cn(C)nc1C
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Compound Formula C20H22FN5O2
Compound Structure
Protein Name
ALK tyrosine kinase receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase STKR family
>
TKL protein kinase STKR Type 1 subfamily
Uniprot ID
Q9UM73
Gene Name
ALK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  2
1
IC50 = 116 nM
   TI
   LI
   LO
   TS
2
IC50 = 1665 nM
   TI
   LI
   LO
   TS