Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-(4-fluorophenyl)-N-(4-methyl-3-morpholin-4-ylsulfonylphenyl)-3-(4-methylphenyl)pyrazole-4-carboxamide
    Show/Hide
 PubChem ID
CID: 90656822
Canonical SMILES
Cc1ccc(cc1)-c1nn(cc1C(=O)Nc1ccc(C)c(c1)S(=O)(=O)N1CCOCC1)-c1ccc(F)cc1
    Show/Hide
Compound Formula C28H27FN4O4S
Compound Structure
Protein Name
 Protein Info 
Bile acid receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 1
>
Nuclear hormone receptor subfamily 1 group H
>
Nuclear hormone receptor subfamily 1 group H member 4
Uniprot ID
Q96RI1
Gene Name
NR1H4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 2490 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 24.3 nM