Brief Information of the Compound and Protein
Compound Name
 Compound Info 
BDBM50249542
    Show/Hide
 PubChem ID
CID: 11213558
SID: 16296087
Canonical SMILES
COc1cc(Nc2ncc(F)c(Nc3ccc4OC(C)(C)C(=O)Nc4n3)n2)cc(OC)c1OC
    Show/Hide
Compound Formula C22H23FN6O5
Compound Structure
Protein Name
 Protein Info 
Receptor-type tyrosine-protein kinase FLT3
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P36888
Gene Name
FLT3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000091 MV4-11
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 10 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Kd = 0.37 nM
2 Kd = 0.54 nM
3 Kd = 0.65 nM
4 Kd = 0.68 nM
5 Kd = 0.71 nM
6 Kd = 1.5 nM
7 Kd = 4.4 nM