Brief Information of the Compound and Protein
Compound Name
N-[7-[5-chloro-4-(3,5-dimethylpyridin-2-yl)pyridin-2-yl]-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-2-yl]-2-methoxyacetamide
    Show/Hide
PubChem ID
CID: 90656306
Canonical SMILES
COCC(=O)Nc1cn2CCN(Cc2n1)c1cc(c(Cl)cn1)-c1ncc(C)cc1C
    Show/Hide
Compound Formula C21H23ClN6O2
Compound Structure
Protein Name
Protein smoothened
Protein Classification
Membrane receptor
>
Frizzled family G protein-coupled receptor
>
Smoothened receptor (frizzled family GPCR)
Uniprot ID
Q99835
Gene Name
SMO
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
IC50 = 650 nM
   TI
   LI
   LO
   TS