Brief Information of the Compound and Protein
Compound Name
[7-[5-chloro-4-(3,5-dimethylpyridin-2-yl)pyridin-2-yl]-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-2-yl]-(3,5-dimethylpiperazin-1-yl)methanone
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PubChem ID
CID: 90656298
Canonical SMILES
CC1CN(CC(C)N1)C(=O)c1cn2CCN(Cc2n1)c1cc(c(Cl)cn1)-c1ncc(C)cc1C
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Compound Formula C25H30ClN7O
Compound Structure
Protein Name
Protein smoothened
Protein Classification
Membrane receptor
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Frizzled family G protein-coupled receptor
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Smoothened receptor (frizzled family GPCR)
Uniprot ID
Q99835
Gene Name
SMO
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
IC50 = 1500 nM
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