Brief Information of the Compound and Protein
Compound Name
N-benzyl-2-(3-(biphenyl-4-yl)-2-((5-(dimethylamino)pentyl)(methyl)amino)-3,4-dihydroquinazolin-4-yl)acetamide dihydrochloride
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PubChem ID
CID: 50898773
SID: 110268210
Canonical SMILES
CN(C)CCCCCN(C)C1=Nc2ccccc2C(CC(=O)NCc2ccccc2)N1c1ccc(-c2ccccc2)cc1.Cl.Cl
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Compound Formula C37H45Cl2N5O
Compound Structure
Protein Name
Voltage-dependent T-type calcium channel subunit alpha-1G
Protein Classification
Ion channel
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Voltage-gated ion channel
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Voltage-gated calcium channel
Uniprot ID
O43497
Gene Name
CACNA1G
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 260 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 41 nM