Brief Information of the Compound and Protein
Compound Name
(3R)-N-[2-(4-bromophenyl)ethyl]-1-(4-methylpyrimidin-2-yl)piperidine-3-carboxamide
    Show/Hide
PubChem ID
CID: 90654571
Canonical SMILES
Cc1ccnc(n1)N1CCC[C@H](C1)C(=O)NCCc1ccc(Br)cc1
    Show/Hide
Compound Formula C19H23BrN4O
Compound Structure
Protein Name
G-protein coupled bile acid receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
>
Steroid-like ligand receptor
Uniprot ID
Q8TDU6
Gene Name
GPBAR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000001 Jurkat Homo sapiens (Human)  1
1
EC50 = 33 nM
   TI
   LI
   LO
   TS