Brief Information of the Compound and Protein
Compound Name
N-(7,7-dimethyl-9-oxo-6,8-dihydrodibenzofuran-3-yl)-2-oxo-1H-benzo[cd]indole-6-sulfonamide
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PubChem ID
CID: 90654865
Canonical SMILES
CC1(C)Cc2oc3cc(NS(=O)(=O)c4ccc5NC(=O)c6cccc4c56)ccc3c2C(=O)C1
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Compound Formula C25H20N2O5S
Compound Structure
Protein Name
Nuclear receptor ROR-gamma
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group F
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Nuclear hormone receptor subfamily 1 group F member 3
Uniprot ID
P51449
Gene Name
RORC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  2
1
IC50 = 7560 nM
   TI
   LI
   LO
   TS
2
IC50 = 11840 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 20270 nM