Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-ethyl-N-[[4-methyl-6-(trifluoromethyl)pyrimidin-2-yl]methyl]-2-oxobenzo[cd]indole-6-sulfonamide
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 PubChem ID
CID: 90654874
Canonical SMILES
CCN1C(=O)c2cccc3c(ccc1c23)S(=O)(=O)NCc1nc(C)cc(n1)C(F)(F)F
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Compound Formula C20H17F3N4O3S
Compound Structure
Protein Name
 Protein Info 
Nuclear receptor ROR-gamma
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group F
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Nuclear hormone receptor subfamily 1 group F member 3
Uniprot ID
P51449
Gene Name
RORC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 410 nM
   TI
   LI
   LO
   TS
2
IC50 = 2570 nM
   TI
   LI
   LO
   TS