Brief Information of the Compound and Protein
Compound Name
N-(6-ethoxy-1,3-benzothiazol-2-yl)-1-ethyl-2-oxobenzo[cd]indole-6-sulfonamide
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PubChem ID
CID: 24906344
Canonical SMILES
CCOc1ccc2nc(NS(=O)(=O)c3ccc4N(CC)C(=O)c5cccc3c45)sc2c1
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Compound Formula C22H19N3O4S2
Compound Structure
Protein Name
Nuclear receptor ROR-gamma
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group F
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Nuclear hormone receptor subfamily 1 group F member 3
Uniprot ID
P51449
Gene Name
RORC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  2
1
IC50 = 930 nM
   TI
   LI
   LO
   TS
2
IC50 = 1350 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 6720 nM