Brief Information of the Compound and Protein
Compound Name
4-[[1-(2,4-dichlorophenyl)sulfonyl-3-hydroxyazetidin-3-yl]methoxy]-2-fluorobenzonitrile
    Show/Hide
PubChem ID
CID: 90665456
Canonical SMILES
OC1(COc2ccc(C#N)c(F)c2)CN(C1)S(=O)(=O)c1ccc(Cl)cc1Cl
    Show/Hide
Compound Formula C17H13Cl2FN2O4S
Compound Structure
Protein Name
Transient receptor potential cation channel subfamily V member 4
Protein Classification
Ion channel
>
Voltage-gated ion channel
>
Transient receptor potential channel
Uniprot ID
Q9HBA0
Gene Name
TRPV4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  2
1
EC50 > 1000 nM
   TI
   LI
   LO
   TS
2
IC50 = 3.8 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 4 nM