Brief Information of the Compound and Protein
Compound Name
N-[5-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]sulfamoyl]-4-methyl-1,3-thiazol-2-yl]acetamide
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PubChem ID
CID: 44241473
SID: 125319187
Canonical SMILES
CC(=O)Nc1nc(C)c(s1)S(=O)(=O)Nc1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F
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Compound Formula C15H13F6N3O4S2
Compound Structure
Protein Name
Nuclear receptor ROR-alpha
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group F
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Nuclear hormone receptor subfamily 1 group F member 1
Uniprot ID
P35398
Gene Name
RORA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 4000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 172 nM