Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-[4-[[4-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]phenyl]methyl]piperazin-1-yl]ethanone
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 PubChem ID
CID: 71470549
SID: 163436077
Canonical SMILES
CC(=O)N1CCN(Cc2ccc(cc2)-c2ccc(cc2)C(O)(C(F)(F)F)C(F)(F)F)CC1
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Compound Formula C22H22F6N2O2
Compound Structure
Protein Name
 Protein Info 
Nuclear receptor ROR-gamma
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group F
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Nuclear hormone receptor subfamily 1 group F member 3
Uniprot ID
P51449
Gene Name
RORC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 1500 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1000 nM
2 Ki = 1000 nM