Brief Information of the Compound and Protein
Compound Name
N-[4-[[3-(3-benzyl-4-oxo-1,2-dihydroquinazolin-2-yl)phenyl]methoxy]phenyl]acetamide
    Show/Hide
PubChem ID
CID: 49789102
Canonical SMILES
CC(=O)Nc1ccc(OCc2cccc(c2)C2Nc3ccccc3C(=O)N2Cc2ccccc2)cc1
    Show/Hide
Compound Formula C30H27N3O3
Compound Structure
Protein Name
Thyrotropin receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Glycohormone receptor
>
Glycohormone receptor
Uniprot ID
P16473
Gene Name
TSHR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL001022 HEK293EM Homo sapiens (Human)  1
1
EC50 = 1860 nM
   TI
   LI
   LO
   TS