Brief Information of the Compound and Protein
Compound Name
3-{(1R)-1-[5-Fluoro-2-(2H-1,2,3-triazol-2-yl)phenyl]ethoxy}-5-(4-methoxypyrimidin-5-yl)pyridin-2-amine
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PubChem ID
CID: 76318350
Canonical SMILES
COc1ncncc1-c1cnc(N)c(O[C@H](C)c2cc(F)ccc2-n2nccn2)c1
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Compound Formula C20H18FN7O2
Compound Structure
Protein Name
ALK tyrosine kinase receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase STKR family
>
TKL protein kinase STKR Type 1 subfamily
Uniprot ID
Q9UM73
Gene Name
ALK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
IC50 = 772 nM
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   LI
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   TS