Brief Information of the Compound and Protein
Compound Name
3-{(1R)-1-[5-Fluoro-2-(2H-1,2,3-triazol-2-yl)phenyl]ethoxy}-5-(1-methyl-1H-pyrazol-5-yl)pyridin-2-amine
    Show/Hide
PubChem ID
CID: 67467673
Canonical SMILES
C[C@@H](Oc1cc(-c2ccnn2C)cnc1N)c1cc(F)ccc1-n1nccn1
    Show/Hide
Compound Formula C19H18FN7O
Compound Structure
Protein Name
ALK tyrosine kinase receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase STKR family
>
TKL protein kinase STKR Type 1 subfamily
Uniprot ID
Q9UM73
Gene Name
ALK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
IC50 = 677 nM
   TI
   LI
   LO
   TS