Brief Information of the Compound and Protein
Compound Name
3-[(1R)-1-[5-fluoro-2-(triazol-2-yl)phenyl]ethoxy]-5-(3-methyltriazol-4-yl)pyridin-2-amine
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PubChem ID
CID: 76318349
Canonical SMILES
C[C@@H](Oc1cc(cnc1N)-c1cnnn1C)c1cc(F)ccc1-n1nccn1
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Compound Formula C18H17FN8O
Compound Structure
Protein Name
ALK tyrosine kinase receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase STKR family
>
TKL protein kinase STKR Type 1 subfamily
Uniprot ID
Q9UM73
Gene Name
ALK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  2
1
IC50 = 249 nM
   TI
   LI
   LO
   TS
2
IC50 = 2650 nM
   TI
   LI
   LO
   TS