Brief Information of the Compound and Protein
Compound Name
4-[2-(4-methoxyphenyl)-1H-imidazo[4,5-b]pyridin-6-yl]-N-methylthiophene-2-carboxamide
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PubChem ID
CID: 76332688
Canonical SMILES
CNC(=O)c1cc(cs1)-c1cnc2nc([nH]c2c1)-c1ccc(OC)cc1
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Compound Formula C19H16N4O2S
Compound Structure
Protein Name
Serine/threonine-protein kinase TBK1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Other protein kinase group
>
Other protein kinase IKK family
Uniprot ID
Q9UHD2
Gene Name
TBK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 851 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 203 nM