Brief Information of the Compound and Protein
Compound Name
(E)-1-[4-(3-ethynylanilino)-8,9-dihydro-7H-pyrimido[5,4-h][1,5]benzoxazepin-6-yl]-4-pyrrolidin-1-ylbut-2-en-1-one
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PubChem ID
CID: 76332332
Canonical SMILES
O=C(\C=C\CN1CCCC1)N1CCCOc2cc3ncnc(Nc4cccc(c4)C#C)c3cc12
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Compound Formula C27H27N5O2
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000220 KB Homo sapiens (Human)  1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS