Brief Information of the Compound and Protein
Compound Name
methyl (1S,15S,17S,18S)-17-ethyl-7-methoxy-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4(9),5,7-tetraene-1-carboxylate
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PubChem ID
CID: 73255
Canonical SMILES
CC[C@H]1C[C@@H]2CN3CCc4c([nH]c5ccc(OC)cc45)[C@](C2)([C@H]13)C(=O)OC
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Compound Formula C22H28N2O3
Compound Structure
Protein Name
Transient receptor potential cation channel subfamily V member 1
Protein Classification
Ion channel
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Voltage-gated ion channel
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Transient receptor potential channel
Uniprot ID
Q8NER1
Gene Name
TRPV1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  3
1
IC50 = 24000 nM
   TI
   LI
   LO
   TS
2
IC50 = 50000 nM
   TI
   LI
   LO
   TS
3
Kd = 19952.62 nM
   TI
   LI
   LO
   TS
CL000058 T-REx-293 Homo sapiens (Human)  1
1
IC50 = 30000 nM
   TI
   LI
   LO
   TS